ABSTRACT
Background: Preterm labour and resulting preterm birth of baby is challenge for gynaecologists
Objective: To compare the efficacy of transdermal nitroglycerine with oral nifedipine in inhibition of preterm labour. Methodology: This experimental study was conducted in the department of Obstetrics and Gynaecology in Sheikh Zayed Medical College/Hospital, Rahim Yar Khan. This study enrolled 60 women with preterm labour, first 30 patients received oral Nifedipine and next 30 patients used transdermal nitroglycerine [NTG] patch. The data was entered and analyzed by using SPSS version 16
Results: Mean prolongation of pregnancy was more with nitro glycerine [30.13+3 days] compared to Nifedipine [29.57+ 6days]. Nifedipine was more successful in prolonging pregnancy beyond 48 hours. Failure of acute tocolysis defined as delivery within 48 hours, was more common with NTG [33.3%] as compared to Nifedipine [23.3%]. Headache was higher in nitrglycerine group [3.3%] compared to Nifedipine group [0%]. The neonatal outcomes in terms of respiratory distress was higher in Nifedipine [76.7%] than Nitroglycrine group [63.3%].There was no statistically significant difference between two groups
Conclusion: Nitroglycerine patch is as effective as Nifedipine in suppression of preterm labour and in prolonging pregnancy
ABSTRACT
Background: First trimester miscarriages are commonly encounted by gynecologists
Objective: To determine efficacy of manual vacuum aspiration in first trimester miscarriages
Methodology: This cross sectional study was carried out in Department of Obstetrics and Gynaecology, Lady Willingdon Hospital Lahore from 1 May to 30 October 2010. 150 patient were enrolled in study fulfilling inclusion criteria and manual vacuum aspiration [MVA] was performed under local anesthesia. Post evacuation ultrasonography was performed in all patients. The data was entered and analyzed by using SPSS version15
Results: Efficacy of MVA was 89.3% and 16% patients has incomplete uterine evacuation. No major complication was noted, except one patient out of 150, has moderate to severe bleeding and 6 has infection
Conclusion: MVA has high efficacy and is associated with less complications
ABSTRACT
Background: Carcinoma cervix is one of the common female cancer worldwide, which has excellent cure rate if diagnosed early
Objective: To determine the accuracy of colposcopy in the diagnosis of early carcinoma of cervix using histopathology as the gold standard
Patients and Methods: Study Design: Comparative cross sectional study
Place and Duration of study: Department of Obstetrics and Gynaecology Unit-1, Sir Ganga Ram hospital, Lahore from 25[th] July, 2006 to 24[th] January, 2007. One hundred patients were included having symptoms of lower genital tract like: chronic vaginal discharge and irregular or post coital bleeding. Women with obvious naked eye lesion of cervix or abnormal Pap smear report were also recorded. Exclusion criteria included pregnant women, asymptomatic women and women on exogenous hormones. Colposcopy findings were noted, along with menstrual, family history and parity. Sensitivity, specifically, positive and negative predictive values were calculated. Data was entered and analyzed by SPSS version 12
Results: The age group ranged from 15-60 years, with Mean +/-SD of 36.7+/-10 years. By age classification the age group 26-35 years were highest in proportion [40%]. Sensitivity, specificity, diagnostic accuracy, positive predicate value [PPV] and negative predictive value [NPV] was found to be 86.6%, 91.7%, 91%, 65%, 97.7%, respectively
Conclusion: Although cervical cancer is a case of significant morbidity and mortality among gynecological malignancies, but with the help of non invasive technique like colposcopy cervical cancer can be detected in its earlier stages where definitive cure is possible. So, it is advocated that colposcopy should become an integral part of all gynecological services, especially in the teaching hospitals as well as in tertiary referral centers of our country